Quality of randomised trials in COPD
نویسندگان
چکیده
منابع مشابه
Quality of randomised trials in COPD.
Randomised trials can provide high-level evidence to inform treatment decisions. Since their quality in respiratory medicine is largely unknown, we assessed the quality of a large set of chronic obstructive pulmonary disease (COPD) trials. As a marker of trial quality, we assessed the procedure and concealment of random allocation, and the conduct of an intention-to-treat-analysis in 344 random...
متن کاملQuality of randomised controlled trials
Editor—The Save European Science campaign (www.SaveEuropeanResearch.org) was launched on 9 December 2003 out of concern for the future of academic and investigator led research in Europe with the advent of the European Union clinical trials directive (see p 240). It was launched from a cancer platform but is inclusive in spirit and has already gained momentum in cardiology, dermatology, and psy...
متن کاملIntroducing “Agreement on what to Measure in Randomised Controlled Trials in Burn Care” Research Project
پروژه پژوهشی "توافق دربارهی پیامدهای قابل اندازهگیری در کارآزمایی های کنترلدار مربوط به مراقبتهای سوختگی" توسط گروهی از پژوهشگران با تجربه، در حوزه سوختگی، زیر نظر دکتر Young از کشور انگلستان در حال انجام میباشد. هدف نهایی از انجام این مطالعه، تهیه و تدوین مجموعهای از پیامدهای اساسی (core outcome set (COS)) است که در گزارش کارآزمایی های شاهددار تصادفی مربوط به مراقبتهای سوختگی باید مور...
متن کاملRun-in bias in randomised trials: the case of COPD medications.
Most randomised trials of newer and established medications in chronic obstructive pulmonary disease (COPD) enrol patients who have already been treated, often with drugs of the same class or even with the very same drugs that are to be studied. Some trials such as UPLIFT evaluated the effect of a drug as an add-on, with patients continuing their existing treatments [1]. Other trials, such as O...
متن کاملCounting, analysing and reporting exacerbations of COPD in randomised controlled trials.
BACKGROUND Clinical trials measure exacerbations of chronic obstructive pulmonary disease (COPD) inconsistently. A study was undertaken to determine if different methods for ascertaining and analysing COPD exacerbations lead to biased estimates of treatment effects. METHODS Information on the methods used to count, analyse and report COPD exacerbation rates was abstracted from clinical trials...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: European Respiratory Journal
سال: 2009
ISSN: 0903-1936,1399-3003
DOI: 10.1183/09031936.00159108